Thursday, November 28, 2019

American Civil War - American Civil War Eastern Theater 1863 to 1865

American Civil War - American Civil War Eastern Theater 1863 to 1865 Previous: War in the West, 1863-1865 Page | Civil War 101 Grant Comes East In March 1864, President Abraham Lincoln promoted Ulysses S. Grant to lieutenant general and gave him command of all Union armies. Grant elected to turn over operational control of the western armies to Maj. Gen. William T. Sherman and shifted his headquarters east to travel with Maj. Gen. George G. Meades Army of the Potomac. Leaving Sherman with orders to press the Confederate Army of Tennessee and take Atlanta, Grant sought to engage General Robert E. Lee in a decisive battle to destroy the Army of Northern Virginia. In Grants mind, this was the key to ending the war, with the capture of Richmond of secondary importance. These initiatives were to be supported by smaller campaigns in the Shenandoah Valley, southern Alabama, and western Virginia. The Overland Campaign Begins the Battle of Wilderness In early May 1864, Grant began moving south with 101,000 men. Lee, whose army numbered 60,000, moved to intercept and met Grant in a dense forest known as the Wilderness. Adjacent to the 1863 Chancellorsville battlefield, the Wilderness soon became a nightmare as the soldiers fought through the dense, burning woods. While Union attacks initially drove the Confederates back, they were blunted and forced to withdrawal by the late arrival of Lt. Gen. James Longstreets corps. Assaulting the Union lines, Longstreet recovered the territory that had been lost, but was severely wounded in the fighting. After three days of the fighting, the battle had turned into a stalemate with Grant having lost 18,400 men and Lee 11,400. While Grants army had suffered more casualties, they comprised a lesser proportion of his army than Lees. As the Grants goal was to destroy Lees army, this was an acceptable outcome. On May 8, Grant ordered the army to disengage, but rather than withdrawal towards Washington, Grant ordered them to continue moving south. Battle of Spotsylvania Court House Marching southeast from the Wilderness, Grant headed for Spotsylvania Court House. Anticipating this move, Lee dispatched Maj. Gen. Richard H. Anderson with Longstreets corps to occupy the town. Beating the Union troops to Spotsylvania, the Confederates constructed an elaborate set of earthworks in the rough shape of an inverted horseshoe with a salient at the northern point known as the Mule Shoe. On May 10, Col. Emory Upton led a twelve regiment, spearhead attack against the Mule Shoe which broke the Confederate line. His assault went unsupported and his men were forced to withdrawal. Despite the failure, Uptons tactics were successful and were later replicated during World War I. Uptons attack alerted Lee to the weakness of the Mule Shoe section of his lines. To reinforce this area, he ordered a second line built across the salients base. Grant, realizing how close Upton had been to succeeding ordered a massive assault on the Mule Shoe for May 10. Led by Maj. Gen. Winfield Scott Hancocks II Corps, the attack overwhelmed the Mule Shoe, capturing over 4,000 prisoners. With his army about to be split in two, Lee led Lt. Gen. Richard Ewells Second Corps into the fray. In a full day and nights fighting, they were able to retake the salient. On the 13th, Lee withdrew his men to the new line. Unable to break through, Grant responded as he did after Wilderness and continued moving his men south. North Anna Lee raced south with his army to assume a strong, fortified position along the North Anna River, always keeping his army between the Grant and Richmond. Approaching the North Anna, Grant realized that he would need to split his army to attack Lees fortifications. Unwilling to do so, he moved around Lees right flank and marched for the crossroads of Cold Harbor. Battle of Cold Harbor The first Union troops arrived at Cold Harbor on May 31 and began skirmishing with the Confederates. Over the next two days the scope of the fighting grew as the main bodies of the armies arrived on the field. Facing the Confederates over a seven mile line, Grant planned a massive assault for dawn on June 3. Firing from behind fortifications, the Confederates butchered the soldiers of the II, XVIII, and IX Corps as they attacked. In the three days of fighting, Grants army suffered over 12,000 casualties as opposed to only 2,500 for Lee. The victory at Cold Harbor was to be the last for the Army of Northern Virginia and haunted Grant for years. After the war he commented in his memoirs, I have always regretted that the last assault at Cold Harbor was ever made...no advantage whatever was gained to compensate for the heavy loss we sustained. The Siege of Petersburg Begins After pausing for nine days at Cold Harbor, Grant stole a march on Lee and crossed the James River. His objective was to take the strategic city of Petersburg, which would cut the supply lines to Richmond and Lees army. After hearing that Grant crossed the river, Lee rushed south. As the lead elements of the Union army approached, they were prevented from entering by Confederate forces under Gen. P.G.T. Beauregard. Between June 15-18, Union forces launched a series of attacks, but Grants subordinates failed to push home their assaults and only forced Beauregards men to retire to citys inner fortifications. With the full arrival of both armies, trench warfare ensued, with the two sides facing off in a precursor to World War I. In late June, Grant began a series of battles to extend the Union line west around the south side of the city, with the goal of severing the railroads one by one and overextending Lees smaller force. On July 30, in an effort to break the siege, he authorized the detonation of a mine under the center of the Lees lines. While the blast took the Confederates by surprise, they quickly rallied and beat back the mishandled follow-up assault. Previous: War in the West, 1863-1865 Page | Civil War 101 Previous: War in the West, 1863-1865 Page Civil War 101 Campaigns in the Shenandoah Valley In conjunction with his Overland Campaign, Grant ordered Maj. Gen. Franz Sigel to move southwest up the Shenandoah Valley to destroy the rail and supply center of Lynchburg. Sigel began his advance but was defeated at New Market on May 15, and replaced by Maj. Gen. David Hunter. Pressing on, Hunter won a victory at the Battle of Piedmont on June 5-6. Concerned about the threat posed to his supply lines and hoping to force Grant to divert forces from Petersburg, Lee dispatched Lt. Gen. Jubal A. Early with 15,000 men to the Valley. Monocacy Washington After halting Hunter at Lynchburg on June 17-18, Early swept unopposed down the Valley. Entering Maryland, he turned east to menace Washington. As he moved towards the capital, he defeated a small Union force under Maj. Gen. Lew Wallace at Monocacy on July 9. Though a defeat, Monocacy delayed Earlys advance allowing Washington to be reinforced. On July 11 and 12, Early attacked the Washington defenses at Fort Stevens with no success. On the 12th, Lincoln viewed part of the battle from the fort becoming the only sitting president to be under fire. Following his attack on Washington, Early withdrew to the Valley, burning Chambersburg, PA along the way. Sheridan in the Valley To deal with the Early, Grant dispatched his cavalry commander, Maj. Gen. Philip H. Sheridan with an army of 40,000 men. Advancing against Early, Sheridan won victories at Winchester (September 19) and Fishers Hill (September 21-22) inflicting heavy casualties. The decisive battle of the campaign came at Cedar Creek on October 19. Launching a surprise attack at dawn, Earlys men drove the Union troops from their camps. Sheridan, who was away at a meeting in Winchester, raced back to his army and rallied the men. Counterattacking, they broke Earlys disorganized lines, routing the Confederates and forcing them to flee the field. The battle effectively ended the fighting in the Valley as both sides rejoined their larger commands at Petersburg. Election of 1864 As military operations continued, President Lincoln stood for reelection. Partnering with War Democrat Andrew Johnson of Tennessee, Lincoln ran on the National Union (Republican) ticket under the slogan Dont Change Horses in the Middle of a Stream. Facing him was his old nemesis Maj. Gen. George B. McClellan who was nominated on a peace platform by the Democrats. Following Shermans capture of Atlanta and Farraguts triumph at Mobile Bay, Lincolns reelection was all but assured. His victory was a clear signal to the Confederacy that there would be no political settlement and that war would be prosecuted to end. In the election, Lincoln won 212 electoral votes to McClellans 21. Battle of Fort Stedman In January 1865, President Jefferson Davis appointed Lee to command of all Confederate armies. With the western armies decimated, this move came too late for Lee to effectively coordinate a defense of the remaining Confederate territory. The situation worsened that month when Union troops captured Fort Fisher, effectively closing the Confederacys last major port, Wilmington, NC. At Petersburg, Grant kept pressing his lines west, forcing Lee to further stretch his army. By mid-March, Lee began to consider abandoning the city and making an effort to link up with Confederate forces in North Carolina. Prior to pulling out, Maj. Gen. John B. Gordon suggested a daring attack on the Union lines with the goal of destroying their supply base at City Point and forcing Grant to shorten his lines. Gordon launched his attack on March 25 and overran Fort Stedman in the Union lines. Despite early success, his breakthrough was quickly contained and his men driven back to their own lines. Battle of Five Forks Sensing Lee was weak, Grant ordered Sheridan to attempt a move around the Confederate right flank to the west of Petersburg. To counter this move, Lee dispatched 9,200 men under Maj. Gen. George Pickett to defend the vital crossroads of Five Forks and the Southside Railroad, with orders to hold them at all hazards. On March 31, Sheridans force encountered Picketts lines and moved to attack. After some initial confusion, Sheridans men routed the Confederates, inflicting 2,950 casualties. Pickett, who was away at a shad bake when the fighting started, was relieved of his command by Lee. The Fall of Petersburg The following morning, Lee informed President Davis that Richmond and Petersburg would have to be evacuated. Later that day, Grant launched a series of massive assaults all along the Confederate lines. Breaking through in numerous places, Union forces forced the Confederates to surrender the city and flee west. With Lees army in retreat, Union troops entered Richmond on April 3, finally achieving one of their principle war goals. The next day, President Lincoln arrived to visit the fallen capital. The Road to Appomattox After occupying Petersburg, Grant began chasing Lee across Virginia with Sheridans men in the lead. Moving west and harried by Union cavalry, Lee hoped to re-supply his army before heading south to link up with forces under Gen. Joseph Johnston in North Carolina. On April 6, Sheridan was able to cut off approximately 8,000 Confederates under Lt. Gen. Richard Ewell at Saylers Creek. After some fighting the Confederates, including eight generals, surrendered. Lee, with fewer than 30,000 hungry men, hoped to reach supply trains that were waiting at Appomattox Station. This plan was dashed when Union cavalry under Maj. Gen. George A. Custer arrived in the town and burned the trains. Previous: War in the West, 1863-1865 Page Civil War 101 Previous: War in the West, 1863-1865 Page | Civil War 101 Meeting at Appomattox Court House While most of Lees officers favored surrender, others did not fearing that it would lead to the end of the war. Lee also sought to prevent his army from melting away to fight on as guerrillas, a move that he felt would have long term harm for the country. At 8:00 AM Lee rode out with three of his aides to make contact with Grant. Several hours of correspondence ensued which led to a cease fire and a formal request from Lee to discuss surrender terms. The home of Wilmer McLean, whose house in Manassas had served as Beauregards headquarters during the First Battle of Bull Run, was selected to host the negotiations. Lee arrived first, wearing his finest dress uniform and awaited Grant. The Union commander, who had been suffering a bad headache, arrived late, wearing a worn privates uniform with only his shoulder straps denoting his rank. Overcome by the emotion of the meeting, Grant had difficulty getting to the point, preferring to discuss his previous meeting with Lee during the Mexican-American War. Lee steering the conversation back to the surrender and Grant laid out his terms. Grants Terms of Surrender Grants terms: I propose to receive the surrender of the Army of N. Va. on the following terms, to wit: Rolls of all the officers and men to be made in duplicate. One copy to be given to an officer designated by me, the other to be retained by such officer or officers as you may designate. The officers to give their individual paroles not to take up arms against the Government of the United States until properly exchanged, and each company or regimental commander sign a like parole for the men of their commands. The arms, artillery and public property to be parked and stacked, and turned over to the officer appointed by me to receive them. This will not embrace the side-arms of the officers, nor their private horses or baggage. This done, each officer and man will be allowed to return to their homes, not to be disturbed by United States authority so long as they observe their paroles and the laws in force where they may reside. In addition, Grant also offered to allow the Confederates to take home their horses and mules for use in the spring planting. Lee accepted Grants generous terms and the meeting ended. As Grant rode away from the McLean house, the Union troops began to cheer. Hearing them, Grant immediately ordered it stopped, stating he did not want his men exalting over their recently defeated foe. End of the War The celebration of Lees surrender was muted by the assassination of President Lincoln on April 14 at Fords Theater in Washington. As some of Lees officers had feared, their surrender was the first of many. On April 26, Sherman accepted Johnstons surrender near Durham, NC, and the other remaining Confederate armies capitulated one by one over the next six weeks. After four years of fighting, the Civil War was finally over. Previous: War in the West, 1863-1865 Page | Civil War 101

Sunday, November 24, 2019

The Countries Involved in World War I

The Countries Involved in World War I The relevance of world in the term World War I  is often difficult to see, because books, articles, and documentaries generally concentrate on Europe and America; even the Middle East and Anzac forces (Australian and New Zealand) are often glossed over. The use of world isnt, as non-Europeans might suspect, the result of self-important bias toward the West, because a full list of the countries involved in WWI reveals a picture of global activity. Between 1914 and 1918, more than 100 countries from Africa, the Americas, Asia, Australasia,  and Europe were part of the conflict. Key Takeaways: Countries Involved in World War I Although most of the battles of World War I occurred in western Europe, many other countries were involved in the events.  Some, like Canada and the U.S., declared war, sent troops, and manufactured armaments.Other countries kept prisoner of war camps or sent infrastructure workers.  Many countries in Africa and Asia were colonies of the large empires and were coerced to help with the war effort.   How Involved Were Countries? The levels of  involvement differed hugely. Some countries mobilized millions of troops and fought hard for more than four years; some were used as reservoirs of goods and manpower by their colonial rulers, while others simply declared war later on and contributed only moral support. Many were drawn in by colonial links: When Britain, France, and Germany declared war, they also committed their empires, involving most of Africa, India, and Australasia, while the 1917 entry of the U.S. prompted much of central America to follow. Consequently, the countries in the following list didnt necessarily send troops, and few saw fighting on their own soil; they either declared war or were considered involved in the conflict, such as being invaded before they could declare anything. Its important to remember, though, that the effects of WWI went beyond this global list. Even countries that remained neutral felt the economic and political effects of a conflict that shattered the established global order. Africa In 1914, 90 percent of the continent of Africa were colonies of the European powers, with only Liberia and Ethiopia retaining independence, and so much of Africas participation was enforced or conscripted. All told, about two million Africans served as soldiers or laborers, and half that total was coercively recruited as carriers or other workers, used to build transportation and other infrastructure projects or perform auxiliary services. The only regions to remain neutral in Africa were Ethiopia and the four small Spanish colonies of Rio de Oro (Spanish Sahara), Rio Muni, Ifni, and Spanish Morocco. Colonies in Africa that were involved in some manner included: AlgeriaAngolaAnglo-Egyptian SudanBasutolandBechuanalandBelgian CongoBritish East Africa (Kenya)British Gold CoastBritish SomalilandCameroonCabindaEgyptEritreaFrench Equatorial AfricaGabonMiddle CongoUbangi-SchariFrench SomalilandFrench West AfricaDahomeyGuineaIvory CoastMauretaniaSenegalUpper Senegal and NigerThe GambiaGerman East AfricaItalian SomalilandLiberiaMadagascarMoroccoPortuguese East Africa (Mozambique)NigeriaNorthern RhodesiaNyasalandSierra LeoneSouth AfricaSouth West Africa (Namibia)Southern RhodesiaTogolandTripoliTunisiaUganda and Zanzibar Americas When they finally joined the war effort in 1917, the United States sent four million men to the Allies. As a dominion of the United Kingdom, Canada sent 400,000 enlisted men, and, like the United States, manufactured armaments, aircraft, and ships. Latin American governments seesawed between neutrality and entry into the war, and Brazil was the only independent South American country to declare war in WWI; it joined the Entente countries- Great Britain, France, and Russia- against Germany and Austria-Hungary in 1917. Other South American nations severed their relations with Germany but did not declare war: Bolivia, Ecuador, Peru, and Uruguay, all in 1917. BahamasBarbadosBrazilBritish GuianaBritish HondurasCanadaCosta RicaCubaFalkland IslandsFrench GuianaGrenadaGuatemalaHaitiHondurasGuadeloupeJamaicaLeeward IslandsNewfoundlandNicaraguaPanamaSt. LuciaSt. VincentTrinidad and TobagoU.S.AWest Indies Asia Of all the Asian countries involved in World War I in some manner, India, a colony of the British Empire at the time, sent the most: 1.3 million troops and laborers went to the imperial war effort. China was officially neutral but provided about 200,000 laborers to the Allied forces to repair tanks. Japan sent 14 destroyers and a flagship cruiser to assist British ships in the Mediterranean Sea. Tiny Siam stayed neutral until mid-1917 and then sent about 1,500 men as pilots, aircraft mechanics, automobile drivers and mechanics, and medical and support staff. Regions in Asia contributing to the war effort were: AdenArabiaBahrainEl QatarKuwaitTrucial OmanBorneoCeylonChinaIndiaJapanPersiaPhilippinesRussiaSiamSingaporeTranscaucasiaTurkey Australasia and Pacific Islands The largest contributors to the war efforts were the large Australian Imperial Force (Australia still being a colony of England at the time), 330,000 soldiers sent to aid the Allies in the Middle East and Germany. Other contributing countries included: AntipodesAucklandAustral IslandsAustraliaBismarck ArchipelagoBountyCampbellCaroline IslandsChatham IslandsChristmasCook IslandsDucieElice IslandsFanningFlintFiji IslandsGilbert IslandsKermadec IslandsMacquarieMaldenMariana IslandsMarquesas IslandsMarshal IslandsNew GuineaNew CaledoniaNew HebridesNew ZealandNorfolkPalau IslandsPalmyraPaumoto IslandsPitcairnPhilippinesPhoenix IslandsSamoa IslandsSolomon IslandsTokelau IslandsTonga Europe Map of military alliances of Europe in 1914. historicair Most of the battles of World War I took place in Europe, and willingly or not, the people of most of the countries were somehow active in the conflict. For the Allies, 5.2 million British men served in the conflict, just under half of the available pool of men aged 18-51; 7.9 million French citizens were called to serve. A total of 13 million German citizens fought in the war between 1914 and 1918.  In the occupied territories, Germany and its allies also coerced civilians into labor: citizens from Italy, Albania, Montenegro, Serbia, Romania, and Russian Poland all had conscripts fighting or assisting with the Entente efforts. AlbaniaAustria-HungaryBelgiumBulgariaCzechoslovakiaEstoniaFinlandFranceGreat BritainGermanyGreeceItalyLatviaLithuaniaLuxembourgMaltaMontenegroPolandPortugalRomaniaRussiaSan MarinoSerbiaTurkey Atlantic Islands AscensionSandwich IslandsSouth GeorgiaSt. HelenaTristan da Cunha Indian Ocean Islands Andaman IslandsCocos IslandsMauritiusNicobar IslandsReunionSeychelles Sources Beauprà ©, Nicolas. France.  International Encylopedia of the First World War. Eds. Daniel, Ute, et al. Berlin: Freie Universitt Berlin, 2014. Web.Badsey, Stephen. Great Britain.  International Encylopedia of the First World War. Eds. Daniel, Ute, et al. Berlin: Freie Universitt Berlin, 2017. Web.Boissoneault, Lorraine. The Surprisingly Important Role China Played in WWI. World War I: 100 Years Later. Smithsonian.  2017. Web.Granatstein, J.L. Canada. International Encylopedia of the First World War. Eds. Daniel, Ute, et al. Berlin: Freie Universitt Berlin, 2018. Web.Johnston, Eric. Japans Little-Known, but Significant, Role in World War I. The Japan Times  (2017). Web.Koller, Christian. Colonial Military Participation in Europe (Africa). International Encylopedia of the First World War. Eds. Daniel, Ute, et al. Berlin: Freie Universitt Berlin, 2014. Web.Rinke, Stefan and Karina Kriegsmann. Latin America.  International Encylopedia of the First World War. Eds. Daniel, Ute, et al. Berlin: Freie Universitt Berlin, 2017. Web. Strahan, Hew. The First World War in Africa. Oxford: Oxford University Press, 2004. Print.

Thursday, November 21, 2019

Marriage among the Somali in Africa Essay Example | Topics and Well Written Essays - 1250 words

Marriage among the Somali in Africa - Essay Example Somalia used to be considered the Land of Punt by the ancient Egyptians (Abdullahi 4). They tended to adore its trees, which were responsible for producing the myrrh and aromatic gum resins frankincense. Punt is mentioned in the Bible, and it came to be known as Cape Aromatica by ancient Romans. Somalia is named for Samale or Samaal the Somali people’s legendary father. Most Somali people are Muslims of Sunni sect, and they share a similar language, Somali. Like all other cultures, the Somali people observe Marriage as a passage rite, as well as a fundamental transformation from childhood to adulthood. Traditionally, Somali marriages have created a bond in men and women, as well as between families and clans. The Somali people’s clan groupings are significant social units. Clan membership plays a vital part in Somali politics and culture and clans are patrilineal. They are divided into sub-clans as well as sub-sub-clans, leading to extended families. Somali marriages us ed to be arranged until recently when things changed. The arrangement occurred commonly between a wealthy older man and a father of the young female he wished to wed. Even in the twenty-first century, in many rural areas these customs still remain valid. The man usually pays a bride price in money or livestock to the female’s family (Gardner and Judy 12). Somali society is ethnically endogamous traditionally. Therefore, in order to prolong ties of alliance, marrying occurs between one ethnic Somali to another ethnic Somali of a different clan. Thus, for instance, a recent study showed that among the 89 marriages contracted by Dhulbahante clan men, 62%, (55) were with Dhulbahante sub-clans’ women. 33.7% (31) were with surrounding clans’ women from other clan families. 4.3 % (3) were with the Darod clan family’s women. Traditionally, Samaal marry someone from outside their family lineage or within the family lineage if it is separated from the male by six g enerations or more (Abdullahi 8). The Arab custom of marrying within a father's family lineage is followed by Saab whereby first cousins often marry each other. After marriage, a Somali bride should live with her husband's family while her own parents provide the household goods and home. However, she retains her family name. The Somali â€Å"community† comprises of a varied and a vast array of social groups, familial bonds, and clans, each of which maintains its own beliefs regarding the concept of marriage. According to some Somalis, a girl is considered appropriate for marrying a provided suitor when she reaches age nine. They believe that, incase a girl has not yet been married, by the time she reaches 15 years the girl may be regarded flawed in some aspect hence viewed as bad luck or an outcast to her family. However, in Somali’s central region, there is a strong belief that a female’s suitability for marriage starts immediately the girl's breasts become no ticeable, despite her age. Though this can lead to an inherently immature and extremely young girl child being married off, it cannot be not regarded as problematic for the â€Å"couple.† in this region Somalis believe that just because a female is young, she is not necessarily unsuitable as a wife. The girl should learn her duties as a wife in the period following her marriage if she got married off at a young age. This dynamic is known as â€Å"

Wednesday, November 20, 2019

The FSISs Public Health Information System Essay

The FSISs Public Health Information System - Essay Example The committee further recommended that FSIS collect extensive information regarding meat and poultry labeling and consumer protection. As stated by the Institute for Homeland Security Solutions (2009), the national security of the United States depends on a safe and secure food supply; food that is free of contamination. In 2006, the Pandemic and All-Hazards Preparedness Act was passed by both the White House and Congress. The Act established a goal of near-real-time information to enhance rapid response to public health threats to minimize their impact. To meet such a challenge, public health and safety organizations need to enhance their ability to collect, analyze, and disseminate health information across the organization. Liu & Wein (2008) and Zink (2004) have raised concerns that it is only a matter of time before the United States begins experiencing instances of major food terrorism. Earlier in this century, Sobel, Griffith, Slutsker, Swerdlow & Tauxe observed that the inform ation environment and informatics tools that were used then tended to follow jurisdiction boundaries. They further observed that these boundaries worked against efforts to reduce inherent latencies. One good example of the effects of these boundaries is the 2008 peanut butter contamination. In November 2008, the Center for Disease Control confirmed clusters of Salmonella Typhimurium (IHSS, 2009). Two months later, investigations associated Salmonella Typhimurium with peanut butter contamination.

Monday, November 18, 2019

Research Paper on Capillaria hepatica lifecycle and effects on human

On Capillaria hepatica lifecycle and effects on human health - Research Paper Example It will also discuss the diagnosis, treatment and preventive measures of disease. Capillaria hepatica is a nematode that causes hepatic capillariasis in several mammals. Rodents were the first host to be described with the infection. Later on, it was discovered that the parasite can infect various mammals including humans (Calle, 1991). Rodents are highly infectious explaining for the global spread of the infection. It has been reported in various countries with China having the highest prevalence of the disease. Until 2000, about 37 cases of human infections have been reported worldwide (Li & Hui-Lin, 2010). The symptoms are nonspecific thus, majority of the cases are misdiagnosed. The parasite causes hepatica capillariasis which is a serious infection of the liver. This occurs both in humans and animals. The adult parasite takes the typical shape of a nematode. The anterior part of the body is narrow while the posterior is broad. The adult female measures about 60 mm long by about 0.20 mm wide and the male is about half as long (Bancroft, 1893). The esophagus occupies about half the body length the females and males a third. The eggs are tapered at the poles. They measure about 0.51- 0.68 mm by 0.30-0.35 mm; resembling those of Trichuris trichura. The dorsal part of the parasite has a copulatory sheath and spicule (Attah &Â  Nagarajan, 1983). Humans get infected following the ingestion of food and water contaminated with the embryonated eggs. The parasite requires only one host to mature from the eggs to the adult. The adult parasite lives in the liver of the host where they lay eggs in the parenchyma. The eggs are not excreted in stool rather they remain dormant until the host dies or the liver is eaten by a predator. These eggs are unembryonated thus are not infectious. They are passed through feces where they are embryonated in the environment (Cox, 1993). Cannibalism plays a vital role in the

Friday, November 15, 2019

The History Of Molecular Modeling Biology Essay

The History Of Molecular Modeling Biology Essay Molecular modeling is a collection of science and art that study molecular structure and function by using computational technique to generate a realistic model of molecule based on molecular properties and behavior. A special computer graphics application and viewer is required to study the image of molecular structure and chemical process. Normally, molecular modeling is applied in field that related to drug design and computational biology who focus on study of molecular structure, dynamic, properties, biological activity (e.g. protein folding, protein stability, protein recognition, and structure prediction, structure determination), and new molecular system design. This is because modeling can support a systematic way to investigate the molecular structure, flexibility and function. The computational approach that used in molecular modeling consists of molecular mechanic, quantum mechanics, and molecular simulation. Molecular mechanic is based on empirical result to model the molecular system through motion of an object. For instance, potential energy is calculated by using force field method. Quantum mechanics is described by using wave function and it is important for understand how the atoms are covalently combine to form molecule. Its example is ab initio and semi-empirical quantum mechanics. Molecular simulation is another computational technique which includes molecular dynamics and Monte Carlo. However, to date, molecular modeling is more concerns to the use of a variety of methods to deduce the atomic information of a system which includes all the approaches mentioned above. To know more about molecular modeling, we are advised to know some of its history so we can make sense of molecular modeling as we know it today. In 1858, Archibald Scott Couper, Friedrich August Kekulà © von Stradonitz, and Aleksandr Mikhailovich Butlerov introduced chemical structure with a structure rule that involves the link of carbons and other atoms. Louis Pasteur modified the molecular structure theory in 1860. In 1865, August Wilhelm Hofmann discovered ball and stick model and color scheme. And Alder and Wainwright performed simulation technique on hard spheres model in 1959. Lifson, Scheraga, Allinger, Levitt, Warshel and others introduced the force field concept in 1960. Whilst in 1970, Rahman and Stillinger described the molecular dynamic simulation of water. In 1971, Protein Data Bank (PDB) was established. In 1977 and 1984, water force field was developed by Berendsen and Jorgensen respectively. At same year, Warshel and colleagues published the concept of protein elec trostatics and enzyme-substrate complex. At late 1980s, high speed computer, program, technology innovation, and a variety of algorithm were introduced. From paragraph above, we only know some important year between late 1850s to 1980s. From 1970s onwards, there is a proposed expectation curve as shown in Figure 1.1. As computational method and technology are more available, the expectation towards biomolecular modeling field was continued to rise especially from 1980s to 1990s. Structure based rational drug design was then introduced. It was expected to replace the less efficient methods. However, unrealistically disappointment was followed. Then scientists undergo a recovery phase where Human Genome Project was introduced and new technology with fast workstation was published. With these, a steady progress of productivity is emerged until today in order to reach the realistic expectation. In addition, it is important to know that the latest molecular modeling trend is focusing on the development and implementation of virtual reality whose enhance the three dimensional visualization. Nowadays, molecular modeling has been altered the way to conduct a research, that is choosing the experiment with highest probability of success before perform it. So, there is a demand to have a better and faster program design. It is important to know that molecular model need not be commercial or costly to prepare, inexpensive materials also possible to produce useful model and result. Question 2: Molecular graphics and molecular viewer If we said that molecular modeling is creation of computational model based on molecular properties and behavior, then molecular graphic is the graphical depiction of molecular modeling. Molecular graphic is a discipline of study molecule through visualization of molecules and their component parts. It is refers to three-dimensional depictions of molecules that made to examine and understand their response during reaction and interaction. To date, molecular graphic has been replaced some function of physical molecule model as it is portability and easy to interact with analysis result. In the early stage of molecular graphic, computer graphic tool was dominated by vector graphical representation based on calligraphic technology. During that time, only line and dot were shown. And main frame computer was required to manipulate the molecular structure before submit to graphic hardware. Until the founded of Molecular Graphics Society (known as Molecular Graphics and Modeling Society today) in 1983 and present of Journal of Molecular Graphics, new graphic techniques, hardware device and graphical software were introduced. This discovery allows the interactivity on the basis of space filling molecular model. As we know that, molecular objects are in three-dimensional structure. So molecular graphic representation (MGR) is concerns to the multi-dimensionality in order to provide more molecular information. Graphical excellence is used as a guideline for the MGR development. It is well designed to present data and it consists of complex idea that able to communicate with clarity, precision, and efficiency. Basically, the graphical display will shows data, induces viewer to have greatest number of idea, makes large data set to be coherent, encourage eyeball technique to compare data by using human eye, integrates statistical and verbal description of a data set, and reveals data at different levels to give more details. There are several types of molecular model that relate to molecular graphic in order to combine the computational technique with graphic art. Here, I will briefly discuss a few types that commonly used. Ball and stick model is the most widely used molecular model. It displays the three-dimensional position of atoms and bonds that link between them. Typically, atom is represented by sphere with specific color and bond is represented by rod. The rod can be rotate to provide the insight of bond flexible. The Figure 2.1 shows the proline in ball and stick model and its structural formula. Black color represents carbon, white represents hydrogen, blue represents nitrogen, and red represents oxygen. Stick model (refer Figure 2.2) is similar to ball and stick model but without ball as it represents all atoms and bonds by using rod with different color scheme. Space filling model (refer Figure 2.2) is a type of  three-dimensional  molecular model  where the  atoms  are represented by van der Waals spheres with different color and join directly to one another. Its measurement scale is the same as the real atom scale. It shows the space that atom occupied instead of shows the chemical bond. Wire frame model (refer Figure 2.3) is similar to stick model which shows the connection of atom by different color scheme but with thinner bond (connector). This model is convenient for drawing large molecules. Chicken wire model (refer Figure 2.4) is another method to visualize molecular model by drawing the polygon mesh on surface. Its shape is similar to the regular  hexagonal  pattern with mesh  structure. Ribbon model (refer Figure 2.5) is a three dimensional schematic molecular model that used to represent protein structure. It shows the path and organization of protein backbone, and serves as visual framework that provides details of atomic structure. Coiled ribbon represents ÃŽ ±-helix,  arrow represents ÃŽ ²-strand, and thin tubes represents loop. It shows the visual basic of molecular structure such as twist and fold. Molecular viewer is the molecular graphic software that used to visualize molecular structure. It is selected based on the size of molecule and the task to do. Here, I will briefly discuss a few types of viewer that commonly used. RasMol is a powerful research tool for visualization of protein, nucleic acid, and small molecules. It is easy to use while able to produce high quality three-dimensional image. It is a free viewing system for PDB coordinate files. Chime is a molecular viewer that modified RasMol code to allow visualization of molecule through web browser. It able to display three-dimensional and interactive molecular model from webpage. Jmol is a Java-based molecular viewer that allows visualization of molecule through web browser (like Chime) or stand-alone computer (like RasMol). It supports many different source files such as PDB format to create molecular model. Cn3D is NCBIs three-dimensional structure viewer. It allows the display of three-dimensional structure, sequence, and sequence alignment with annotation and alignment editing feature from NCBIs Entrez. Swiss PDB Viewer or DeepView is a molecular viewer that provide user friendly interface which allows analyzing several proteins or multiple models at same time. It supports alignment which based on individual residue, main chain, or entire protein. It also can align different homologous protein structure. It can be used as a helper application for browser. Visual Molecular Dynamics (VMD) is designed for visualization of large structure molecule such as protein and lipid. Except visualization, VMD also can analyze molecular dynamic simulation, act as graphical front end by display and animate molecule, and sequence browsing. Question 3: Protein structure with reference to hemoglobin and the prion protein Protein structure is biomolecular structure of protein molecule which made up of amino acid polymers. It is critical to its activity and biological function. X-ray crystallography  and NMR spectroscopy are technique that used to determine the protein structure. Basically, the complex protein structure is characterized into four levels of organization (refer Figure 3.1). Primary structure of protein is a linear sequence of amino acid structural unit that held together by peptide bond. It is starting from amino terminus (N) and end with carboxyl terminus (C). The sequence of amino acid will determines primary structure of protein. Change in a single position of amino acid will alter the function and activity of protein, some might cause disease. Secondary structure of protein is local conformation of polypeptide chain. It defined by  the pattern of hydrogen bond that formed between peptide backbones. The polypeptide folds locally into stable structure will form alpha helix, beta pleated sheet, and turn conformation. Tertiary structure of protein is a global three-dimensional structure that formed when secondary structures are folded in three-dimensional space. This folding is triggered by hydrophobic interaction and stabilized by hydrogen bond, van der Waal interaction, disulfide bond, and charge-charge interaction. Tertiary structure can be organized by more than one domain. Domain region can be alpha helix, beta sheet or mixed. Tertiary structure refers to each individual domain as well as to the complete configuration of whole protein. Whilst motif is small structure that plays important role in protein prediction. Quaternary structure of protein refers to regular association of more than two polypeptide chains that fold and coil to form a complex. The interaction between subunits can be identical or different. Quaternary structure is known as a stable three-dimensional structure of multi subunit protein. Hemoglobin is example of protein quaternary structure that found in red blood cells who acts as oxygen transport molecule. It carries oxygen from lung to release in tissue, and binds to carbon dioxide in tissue then releases back to lung. This process is characterized by cooperative interaction of polypeptide chains (subunit) by change their structure to make hemoglobin to be properly function. Hemoglobin (Figure 3.2) is an allosteric protein. It is a tetramer that consists of two types of subunits, two ÃŽ ±-chains and two ÃŽ ²-chains that held together by non-polar interaction and hydrogen bond. Each subunit is arranged as alpha helix structural segment and forms a hydrophobic cleft to allow the attachment of a heme  prosthetic group that consists of an iron atom who acts as oxygen binding site. Each of the subunits can carry one molecule of oxygen. Actually, there has no contact between same type of chain, that is alpha-alpha chain, and beta-beta chain. The contact region occurs between alpha-chain and beta-chain such as alpha1beta1  and alpha1beta2. The alpha1beta2  contact region acts as a switch between deoxy (T) structure to the oxy (R) structure. At T structure or tense state, binding of oxygen is difficult. While oxygen is favored at R structure or relax state as binding of oxygen will trigger the affinity of next oxygen to hemoglobin. Transition from T structure to R structure is triggered by stereo chemical changes at the heme group as shown in Figure 3.3. Like other proteins, hemoglobin is created by DNA in body. Alteration of amino acid will cause blood related disorder such as sickle cell anemia. This disease is results from a mutation at sixth residue in the ÃŽ ² hemoglobin monomer. Proteinaceous infectious virion (prion) is an infectious protein that causes neurodegenerative disease such as Scrapie and Bovine Spongiform Encephalopathy (BSE) in mammal, and Creutzfeldt-Jakob (CJD) and Kuru in human. Prion is known as an infectious agent that infects protein, without the transfer of nucleic acid genome, and it causes other proteins to be misfolded. Proteinaceous infectious particle (PrP), a normal cellular protein, consists of around 250 amino acids is found in our body whose involve in the spread of prion disease. Prion theory states that PrP is sole causative agent of prion diseases. If prion is in normal or stable shape (PrPc), it will not cause disease. Whilst if prion is flipped and folded into abnormal conformation (PrPsc), it will cause disease as it induces other proteins to change their conformation and becomes PrPsc as well. This translation is an exponential process where ÃŽ ±-helical and coil structures are refolded into ÃŽ ²-sheet. PrPc  is the endogenous form of prion protein (PrP), while PrPsc  is the misfolded form of PrP. PrPc and PrPsc are known as protein isoform with tertiary structure characteristic. They are categorized as same protein but with different conformation as their folding region is different as shown in Figure 3.4. PrPc contains more ÃŽ ±-helical and coil structure  and PrPsc has more ÃŽ ²-sheet structure. Prion structure is extremely stable. It is highly resistant to denaturation either by heat, ultraviolet light, or radiation. This characteristic makes prion difficult to be eliminated. Furthermore, prion comes in different strains. Each of the strain has slightly different structure. In other words, there has no effective treatment to fight with prion diseases. Question 4: Protein databases Database is an organized collection of data which allows the convenient access of user. Database can be classified into a variety of type. Here, we only focus on the protein data type. There are three types of protein database, that is protein structure database, protein sequence database, and protein motif database. Before discuss the three types of databases, I would like to briefly describe Protein Data Bank (PDB) which is the primary protein database. Protein Data Bank (PDB) is a worldwide repository of three-dimensional structural data of biological macromolecules. Until March 12, 2013, there are 88837 structures in PDB, in which 82224 are protein structure or 92.56% of PDB structure is protein. All the protein structures are obtained through x-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, cryoelectron microscopy (cryoEM), hybrid technique, and other experimental method. Since 1971, PDB is under the management of Bookhaven. Until 1999, Research Collaboratory of Structural Bioinformatics (RCSB PDB) takes over this task. In 2003, Worldwide PDB (wwPDB) maintains and formalizes the international collaboration by involve RCSB PDB (USA), PDB Japan (PDBj), PDB Europe (PDBe), and Biological Magnetic Resonance Data Bank (BMRB) as members of wwPDB. They act as distribution centers of PDB data. PDB acts as a very important resource to organize and share molecule structure data especially in structural biology area. It serves as a global community to allow scientist to share their research. Currently, the newly determined protein structure will be deposited into PDB data before the scientific paper is published. Except three-dimensional database, PDB also known as primary database for protein structure information. Derived or secondary database will use the PDB data and categorize it in a different way based on their own classification. Protein structure database groups protein based on the similar protein structure and common evolutionary origin. Structural Classification of Proteins (SCOP), CATH, and DALI Domain Dictionary (DDD) databases are the three main protein structure classification databases. But here I will only discuss SCOP and CATH. SCOP is a repository that organizes protein structure hierarchically based on their structure and evolutionary origin. The classification of SCOP is manually. With assistant of computer tool, SCOP able to visual and compare the protein structure consistency. The latest version of SCOP is 1.75 that released on June 2009 with 38221 PDB entries and 110800 domains. The source of protein structure is from Protein Data Bank. The classification of SCOP has six levels that are class, fold, superfamily, family, protein, and species. There are eleven classes in SCOP hierarchy which differentiate by fold type: alpha ÃŽ ±, beta ÃŽ ², alpha and beta (ÃŽ ±/ÃŽ ²), alpha plus beta (ÃŽ ±+ÃŽ ²), multi-domain protein, membrane protein, small protein, coiled coil protein, low resolution structure, peptide, and designed protein. Between the eleven classes, only the first seven classes are known as true class and others serve as place holder for protein domain that have not been classified. Proteins are classified into group based on their structure similarity. The unit of classification is protein domain. The shape of domain is known as fold. Proteins share common fold if they have same major secondary structures in same arrangement and same topological connections. Superfamily is probable has common evolutionary origin which share common fold and perform similar function. Family shows a clearly evolutionary relationship of proteins with more than 30% sequence identity. Protein level will connect proteins through similar function and structure. The last level, species, is grouped according to unique sequence. CATH is a semi-automated protein structure classification in which the protein domain is classified based on class (C), architecture (A), topology (T), and homologous superfamily (H). The latest version of CATH is 3.5 that released on September 20, 2011 with 51334 PDB entries, 173536 CATH domains, and 26226 CATH superfamilies. CATH has four classes, they are alpha, beta, alpha and beta, and few secondary structure. The class of protein domain is determined by its secondary structure composition. Architecture level describes the overall shape of domain structure that determined by secondary structure orientation. Then, domain will be grouped into topology level based on secondary structure shape and connectivity. Homologous superfamily level will then grouped protein domains together based on similar structure, function, and has common ancestor. Protein sequence database can be divided into manually and automatically annotated database. UniProtKB/SwissProt and Protein Information Resource-International Protein Sequence Database (PIR-PSD) are example of manually annotated database. UniProtKB/TrEMBL and NCBI GenPept are example of automatically annotated database. Here, I will discuss the UniProt Knowledgebase (UniProtKB) as example. UniProtKB is a protein sequence and functional information database. The data type that captured in is known as protein annotation. UniProtKB consists of two sections: UniProtKB/SwissProt which can be reviewed and UniProtKB/TrEMBL which cannot be reviewed. Most of the sequence in UniProtKB is derived from International Nucleotide Sequence Database (INSD) and some from PDB database. All these sequences will be automatically added into UniProtKB/TrEMBL. Then the TrEMBL records can be manually selected to be integrated into SwissProt record. UniProtKB/SwissProt is a high curated and non-redundant protein sequence database. The release 2013_03 of March 6, 2013 has 539616 sequence entries. It combines the experimental result, computational analysis, and scientific literature in one entry. It provides all relevant information about the searched protein as the sequence form same gene and same species are merged into same entry. Its file format such as FASTA is downloadable by public. UniProtKB/TrEMBL is a high quality computational analyze and redundant protein sequence database. That means, TrEMBL is computer annotated supplement to SwissProt but with multiple entries for sam eprotein. The release 2013_03 of TrEMBL on March 6, 2013 has 32153798 sequence entries. However, its entry is not redundant to SwissProt. Therefore, the entry of UniProtKB on release 2013_03 will be the combination entry of SwissProt and TrEMBL that is 32693414. Protein motif database also known as pattern and profile database is secondary database that derived from conserved pattern obtained from multiple sequence alignment. It is useful for the classification of protein sequence into family level. PROSITE and BLOCKS are example of motif based database. PROSITE is a protein domain, family and functional site database which comprise of biologically significant protein site, pattern, and profile. It analyzes protein sequence for known motif. PROSITE classification is based on observation. Similar protein sequence will be group into family. And protein domain is classified based on families that share common ancestor or has functional attribute. PROSITE records give the information of structure and function for a particular protein. It is part of the  ExPASy  proteomics  analysis servers and it used the annotation of domain features of SwissProt entry. Up to date, the latest version is release 20.91 of March 4, 2013 with 1661 entries, 1308 patterns, 1053 profiles, and 1057 ProRule. ProRule is the case rule that provides extra information about function and structural of critical amino acids. For instance, it contains the information related to biologically meaningful residue such as active sites, co-factor-binding sites,  and post-translational  modification sites. It helps the protein function determination. And it able to generate annotation automatically based on the PROSITE motifs. PROSITE database is used when identify the possible function of newly discovered protein, and determine activity of known protein. We also can derive a signature or conserved sequence from protein in order to classify protein. This is because each PROSITE signature is linked to an annotation document, where has all related information of the particular protein. PROSITE offers tool that can function for motif detection and protein sequence analysis. The most common application or archive is fingerprint that act as evidence to identify an individual. Appendix: Figure 1.1: Expectation curve for biomolecular modeling and simulation File:L-proline-3D-balls.pnghttp://upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Prolin_-_Proline.svg/121px-Prolin_-_Proline.svg.png Figure 2.1: Ball and stick model of proline Structural formula of proline Space filling model Stick modelhttp://www.rsc.org/ej/NJ/2003/b206570n/b206570n-f3.gif Figure 2.2: Stick model (left) and space filling model (right) of proline http://class.fst.ohio-state.edu/FST822/aa/btwf.gif Figure 2.3: Wire frame model http://upload.wikimedia.org/wikipedia/en/thumb/4/4f/DMT_chicken_wire_mesh.png/227px-DMT_chicken_wire_mesh.pnghttp://upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Tubby-1c8z-pymol.png/160px-Tubby-1c8z-pymol.png Figure 2.4: Chicken wire model with stick model Figure 2.5: Ribbon model http://www.piercenet.com/media/ProStructureFig1.gif Figure 3.1: Four levels of protein structure Diagrammatic representation of the structure of hemoglobin Figure 3.2: Hemoglobin http://jr.stryker.tripod.com/images/TransitionRT.jpg Figure 3.3: Conformation transition from T structure to R structure PrPsc PrPcPrion structure Figure 3.4: Prion protein in abnormal conformation, PrPsc (left) and prion protein in normal conformation, PrPc (right)

Wednesday, November 13, 2019

Urban Safari :: Free Essay Writer

Urban Safari There are times when having a brother with twenty more years of age, experience, and wisdom, can adversely effect your credibility. This is especially true at nine years old. I found this to be the case one Christmas day many years ago when my brother Tom came home for the holidays. It appeared to be the start of a special Christmas, for my brother was coming to visit. I was even more excited than usual for a nine-year-old boy at this time of year. I wondered what new presents would be under the tree? In the past, Tom always got me such neat stuff. I could hardly wait to start shaking the gifts and guessing. As usual, I was up before dawn, tearing into my gifts with all the fervor with which the drowning seize life preservers. My folks, along with my brother, had now joined me in the gift-opening ceremony. Saving the best for last was out of the question; it was the gift from my brother that I tore into first. My dreams had come true. My prayers were answered. There it was, bigger and shinier than anything in the display case of any Western Auto store in the world. It was a B B gun. Finally, I had entered the ranks of the big kids. The prestige of such a gift! I anticipated the glory of shooting my first bird. This was truly a present for a twelve years old, maybe even a teenager. While reveling in my grandeur, I hadn't noticed that my Mother was watching with obvious disapproval. Apparently she had other plans for the B B gun. "You can't shoot that thing in the yard!" she barked. "You'll have to go to the riverbed." With those words, I was instructed to leave the B B gun under the tree with the less attractive presents. "You can open your other gifts now. Tom will watch you while we go visit Auntie Mabel, and don't forget, leave the B B gun alone," Mom ordered. No sooner than they were out the door my brother grabbed the gun and headed towards the back yard. "Where’re you going?" I asked. "To test your gun out before Mom and Dad get back" was his reply. I thought this was a grand idea. Our back yard was full of potential targets. My brother's first choice was two cases of empty mason jars my Mom used for canning fruit.

Sunday, November 10, 2019

Importance of Gwadar Port for Pakistan

Selection of Gwadar for construction of Deep Sea Port. While carrying out feasibility study for development of Gwadar port both Karachi and Bin Qasim were also considered for such development but found not attractive to major shipping agencies due to remoteness from main shipping routes, limitations of draft and comparatively long turn around time. Due to these reasons Gwadar was selected as the site for 3rd commercial port for Pakistan. Geo-Strategic Importance Gwadar port is located about 267 NM West of Karachi. Because of its ideal location at the mouth of gulf and opposite strategic choke points of Strait of Hormuz and Gulf of Oman the port is visualized to become a regional hub serving incoming and out going commercial traffic of Middle East and Gulf countries. The new port of Gwadar will supplement Karachi Port and Port Qasim. It will attract transit and trans-shipment trade from over twenty countries including Srilanka, Bangladesh, Oman, UAE, Saudi Arabia, Qatar, Iraq and Iran. These countries may open their warehouses in Gwadar for export of goods and storing of imported goods for later shipment to their countries. Non Quantifiable Benefits of Port. Details of indirect non quantifiable benefits which the people of region will get and would accrue to the national economy from this port. Duty Free Port & Free Economic Zone/Incentives. Keeping in view the significance of Gwadar port, the government has declared Gwadar as a Duty Free Port and Free Economic Zone. A separate allocation of one billion rupees was made in the budget for the fiscal year 2004-2005 for the construction of the export zone and Gwadar industrial city. This has greatly accelerated the pace of development in the area. The other incentives announced by Govt are summarized as under: Positive approach towards private sector involvement. Infrastructure development on BOT/BOO basis. 100% profit repatriation. Tax holidays for ten years from date of commencement of commercial operations. 100% profit repatriation. Ownership rights. Flexible labour regulations. Subsidy on utilities. Complete exemption from duty & sales tax on imported plants & machinery for 10 years. Capital gains will be exempted from tax for 5 years. No local octroi or export tax leviable by local Govt. Access to CARs. Gwadar Port located in proximity of Arabian Gulf and Central Asian Republics provide it unique opportunity to serve both. Pakistan needs to capitalize on them through better diplomatic ties with Arab states and CARs. It is therefore anticipated that oil reserves and other resources of CARs would gradually become the focus of world attention in coming years. However, in case of â€Å"exports to and from CARs† a peaceful and stable Afghanistan is must. The port will also help in promoting trade with Gulf States possessing 63% of world’s oil reserves and will prove instrumental in promoting trans-shipment essentially of containerized cargo besides unlocking the development potential for hinterland. The most important factor that makes Gwadar Port strategically unique is the location with respect to other major ports in the region, which are all located on the other side of the sea. Gwadar port being towards north can easily provide services and facilities to CARs, Afghanistan and China. Upcoming Fishing Harbour/Industry. Planned fishing harbour/industry linked with this port will facilitate efficient exploitation of our 960 KM of long coast which would give boost to fish and crab exports and would promote food processing industries as well. Gwadar could also be a potential source of gas and oil exploitation. [1] These areas clearly indicate the vast potential which should be exploited and will help contribute towards national economy. Instability in Gulf. Gulf region and CARs contain one of the largest oil and gas resources of the world respectively. Gulf countries in particular, have capitalized on it by constructing major commercial centers with bulk port facilities. Pakistan, could not cash on this opportunity earlier due limited resources which Gulf countries did and so have well established ports these days. Gulf presently is badly exposed to world due instability in region and in case of blockade of Gulf due to any reason, the Gwadar port would become more important due to only choice left. Beside this, sour relations of Iran with western countries and her territorial disputes with Iraq are enough reasons for international community to opt for Gwadar rather than any Iranian port in future. Gwadar Port is therefore expected to act as a vital link to China, Afghanistan and Central Asian Republics throughout the year. Due to these factors Gwadar is going to be the necessity of major shipping competitors as it is the most efficient route to Indian Ocean for world markets. Gwadar Port can therefore become a viable option for wor ld community due to the following reasons: It is not within Gulf, thereby reducing chances of being blocked. It provides shortest access to the land locked Afghanistan and CARs. It is located in close proximity of other regional ports of the Gulf. Trans-shipment of Bulk Cargo. Oil Storage, Refinery and Petrochemical related industries/installations. Export processing and Industrial Zone. Export of minerals and live stock. Services ie hotel accommodation, tourism etc. Fishing industry. Ship repairs and Ship building. Construction of Warehouses and Storages. Beach Industries. Port Related Facilities. Construction of under mentioned facilities/industries is directly linked with the construction of Gwadar Port and will provide employment opportunities for its locals and the region. Trade pact with Tashkent. Considering importance of trade from CARs vis -a-vis up coming Gwadar port. Govt of Pakistan (GOP) has very rightly concluded a trade pact with Tashkent. In this Pakistan and Uzbekistan have agreed to enter into a trilateral transit trade agreement with Afghanistan to benefit from the Gwadar port facility and land routes. As per the joint communique issued after meeting of reps of both sides on 29-30 Dec 2005, a ‘Joint Ministerial Commission’ has been formed to formulate details/trade quantum and the modus operandi. Development Plans/Investment Opportunities For Balochistan By making Gwadar the pivot of regional trade, Pakistan will also attract considerable investment into its most under developed province. These funds will allow construction of roads and railways, linking the coastal region with rest of the Pakistan, Iran and Afghanistan and will also, facilitate cultivation of vast regions and exploration of natural resources. This would ultimately help socio-economic uplift of locals through various development projects. The government on 3 October, 2004 has also announced Rs 3. 00 Bn grant for speeding up development activities for overall uplift of Balochistan. Beside these the development of Gwadar port would also benefit the overall economy of province/country and will unlock its potentials. It is anticipated that around 2. 5 million people will get jobs with start of this project. The government is setting technical training centres in area to train people. Although Gwadar is comparativ ely free from tribal influence, however people of area have two major concerns in their minds. Firstly, influx of people from rest of the country may throw them in minority. Secondly, local population lacks in education and other skills, which may affect their career prospects. They have a fear that people coming from other areas may grab the major share of economic opportunities. General public therefore show a resentment against government policies in form of bomb blasts and demonstrations/destruction of sui gas installation etc, however once economic lifts become visible then people would certainly realise their short sightedness. Oil Factor and the Alternate Port. Pakistan’s present population is arround160 Million. With the present growth rate of population, the country’s oil needs are increasing continuously as well. The fact that our dependence on POL gets further compounded as most of our defense needs are also met through it. National oil reserves are also dependent on the continuous POL from abroad. The war stamina depends on the availability of POL to armed forces for effective fighting. Therefore, keeping in mind the importance of SLOCs for provision of uninterrupted oil supply, Gwadar port would provide much-needed alternate for Karachi/ Qasim ports.

Friday, November 8, 2019

The role of anti-semitism for the final solution essays

The role of anti-semitism for the final solution essays The stage was being set throughout Europe in the late 19th century with anti-Semitism running in the veins of most Germans and other European nations. This answer to the Jewish Question was to be addressed by Heydrich and Himmler at the Wannsee conference in their Final Solution. At the turn of the 19th century, much of the common outlook of Jews in populist Germany held the belief that all economic woes of the times were due to the prevalence of Jewish businesses. Many Germans held the belief that one day, the Jews will rise up and dominate Germany and cast out any traditional German values. One of the first anti-Semitic rises came out of rural Germany through Otto Boeckel who had believed that Jews were the blood enemies of Christ (Weiss p.99). Jews were the major moneylenders for many rural Germans who, during the 1870s, suffered through a depression. Many had lost their land and others had to go to Jews for loans with outlandishly high interest when banks would turn them away due to high risk. In cities, many independent retail establishment owners were big supporters of the anti-Semitic rallies. Jews started mass retail stores that could out sell and outbid many prices of family run businesses in Germany. This caused many family businesses t o go into bankruptcy. Glagau, Stoecker, Boeckel, and Marr were just some of the voices speaking for populist Germany. Nationalism and elections were the major concerns among the German elite in the late 1800s. It was a feeling within the German elite that Jews had other motives that did not include an allegiance to Germany. With so many international ties, how can Jews be true to the German culture? Anti-Semitism became an essential component of a German nationalist. Reversing the rights of Jews was a priority of Conservatives. Conservatives embraced and underscored anti-Semitism when it served them best. Conservatives found that...

Wednesday, November 6, 2019

ACT Score Ranges Understand Your Score vs. Class Grades

ACT Score Ranges Understand Your Score vs. Class Grades SAT / ACT Prep Online Guides and Tips Are you wondering what the highest and lowest possible scores you can get on the ACTare? And, once you receive your score, what does it mean? Many people find it difficult to understand their ACTscore because the exam doesn't usethe same kinds of grades your classes do. In this guide, we've converted ACTscores into class grades to make them easier for you to understand. What'sthe Total Range of ACT Scores? For each section of the ACT, the lowest score you can get is a 1, and the highest score you can get is a 36. The ACT contains four required sections, English, Math, Reading, and Science, and scores from each of those sections are then averaged to get a total composite score for the entire exam. The range of the composite score is also 1-36. However, that still doesn't tell you all the information you need to know. This is because it's quite uncommon for someone to get a perfect score of 36 or a low score of 1 on the ACT. Also, you're probably more used to letter grades, like A- or B+, because that's whatyou see in class. To give you a better understanding of the ACT, we've converted ACT scoresinto letter grades as well asnumericalclass grades, like 85% or 55%, that you've likely seen throughout your time in school. How Can You Interpret Your ACT Score? In the table below, we've mappedACT scores to numerical and letter class grades. We thenexplain how to interpret the results and also how we created the table. In the final section of this guide, we also discuss what a good ACT score is. Conversion of ACTScores to Class Grade Equivalents ACT Composite Score Numerical Class Grade Letter Class Grade 36 100.0 A+ 35 99.9 A+ 34 99.8 A+ 33 99.6 A+ 32 99.3 A+ 31 99.0 A+ 30 98.5 A+ 29 98.0 A+ 28 97.4 A+ 27 96.6 A 26 95.7 A 25 94.7 A 24 93.5 A 23 92.1 A- 22 90.6 A- 21 88.9 B+ 20 87.2 B+ 19 85.5 B 18 83.7 B 17 81.5 B- 16 78.7 C+ 15 75.5 C 14 71.6 C- 13 64.1 D 12 45.1 F 27.3 F 10 15.9 F 9 9.9 F 8 6.4 F 7 4.0 F 6 2.5 F 5 1.5 F 4 0.8 F 3 0.5 F 2 0.3 F 1 0.0 F How can you use this table? For example, say you got a 17 on the ACT. You'd then want to find this row: ACT Composite Score Numerical Class Grade Letter Class Grade 17 81.5 B- From the table, we can see that getting a 17 on the ACT is roughly equivalent to getting a score of 81.5% or a letter grade of B- for a class. What DoesThis Table Really Mean? Put simply, the above table takes ACT scores and converts them to class grades. This gives you a rough idea of what letter grade or percentage you would have gotten on the ACT if the exam had used those types of scoring methods. Class grades are familiar to you because you've used them your whole life, but you may not have any experience with the ACT grading scale. The table takes information you may not completely understand and converts it to something you're more familiar with. More precisely, the above table convertsACT scores to class grades based on percentiles. These percentiles were calculated based on scores of previous ACT exam-takers. The class grades percentiles were based on a large academic survey of grading trends in college (which typically closely match high school grades). So, to go from an ACT score of 17 to a class grade of a B-, we found the ACT percentile for 17, then used the survey to determine what letter grade corresponded to that same percentile. Things to Note inthe Table First, note that the distribution ofACT scores and their class grade equivalents are quite different. At the top of the ACT scale, a 36 and a 28 are 8 points apart, yet, after the conversion, they all map to an A+. That's not a typo; both a 36 and a 28 are equivalent to an A+. Why is this true? It's due to the fact that classes often don't do a great job of differentiating between great students andtruly stand-out ones. In a hypothetical class of 20 students, you might have two people earn an A+. That may seem like a small number at first, however; if that same class represented all the students in the US, only two would score a 28 or above on the ACT. This is one of the reasons the ACT is very useful to colleges, particularly highly selective colleges, because it distinguishes between great students and the very best. Another thing to note is that both class grades and ACT scores do a good job of resolving middle-of-the-pack students.Ifyou go from an ACT score of 13 to a 22 just a range of 9 that's equivalent togoing from a straight D to an A-. For students who are about average in their class or a bit below, both ACT scores and class grades have solidresolution. You may also have noted that neither ACT scores nor class grades begin at zero. Why not? Think about what you know about grading patterns and scores you and your classmates have received. When did you last hear of someone getting a 10 out of 100 as their final class grade? Failing grades are given out less than 4% of the time for class grades. Similarly, when did you last hear of someone getting less than a 10 on the ACT? Neither case is common. Even though, technically, the lowest ACT score is a 1, less than 1% of people taking the ACT get lower than a 10.Therefore, it's more realistic tothink of the ACT as starting from 13, not 1. Can You Really Convert ACT Scores to Class Grades? Yes, it's completely possible to convert ACT scores to class grades; however, it's not an exact science, and there are a few things you should be aware of. First, remember that ACTsand your school classes don't testthe same thing. The ACT is a multiple-choice exam takenin one sitting. Classes, on the other hand, require hours of learning and schoolwork over a long period of time. Additionally, you take the ACT alone, but in your classes you work with teachers and classmates every day. Because the two measure very different things, getting a B- in a class does NOT automatically equala 17 on the ACT, and vice versa. Additionally, class grades aren't as rigorous as the ACT. If you got an A- in a class, would you consider that a good grade? If half the class got an A or an A+, then your A- would be considered a bad grade. Conversely, if you were the only person to get an A in that class all year, that A- would be a great grade. Therefore, you shouldn't view the conversion too rigidly. However, those notes aside, you're correct if you think about the table as "lining up," say, different varieties of races at a track meet. For example, you can't compare someone's performance in the 100-meter dash with a marathoner, but you could say that someone who completed the 100-meter dash in 10 seconds was at an Olympic level, while 2 hours 10 minutes would also be considered an Olympic level marathon time. What’s Next? Not sure what ACT score you should be aiming for? Read this guide to figure out your target ACT score. Want to begin or continue prepping for the ACT? We have a guide that explains every single question type on the ACTso that you're completely prepared for the test! Looking for an easy way to boost your ACT score? Learn aboutthe most common mistakes students make when guessing on the ACTand how you can avoid them. Want to improve your ACT score by 4+ points? Download our free guide to the top 5 strategies you need in your prep to improve your ACT score dramatically.

Monday, November 4, 2019

Conflict Management Styles Paper Research Example | Topics and Well Written Essays - 750 words

Conflict Management Styles - Research Paper Example n this paper, we will discuss different ways to handle conflicts along with the approaches that managers and employees use in my organization for the same purpose. There many approaches which one can use to handle workplace conflicts. Some of the most effective approaches include forcing, accommodating, avoiding, compromising and collaborating. Let us discuss all of them in some detail in order to know the way organizations can use them for conflict management. Forcing is one of the five major methods of conflict management. However, people usually use this method as the last alternative when there is no other way to reach a resolution. Managers often use this method to show their power and authority. Although this method helps people in reaching a quick resolution, but it puts an adverse impact on the relationship that a person has with another person involved in the conflict. Accommodating is a technique using which one conflict party accommodates the concerns of the other party involved in the conflict. Although this technique is useful in resolving the conflicts, but there are also some disadvantages of using this technique. For example, a party involved in conflict can try to take illegitimate advantage of the accommodating approach of the other party. Avoiding is a technique using which a person tries to avoid the issue because of some reasons. In some situations, the issue is not so important that a conflicting party should resolve it whereas, in some situations, a party involved in the conflict does not see any chance of getting the demands met. In some situations, one conflicting party is unable to manage the conflict properly and prefers to stay back from the conflict. â€Å"In the avoiding mode, a business professional is low on assertiveness and low on cooperation† (Tanner, 2010). Compromising is a technique using which all parties involved in the conflict cooperate to reach a mutual agreement. This technique is useful where the intent is to reach

Friday, November 1, 2019

Early Chinese Funerary Art Essay Example | Topics and Well Written Essays - 750 words

Early Chinese Funerary Art - Essay Example Excavations at B'ei-li-kang near Luo-yang date materials found at that site to 6000-5000 B.C." (Pearson Education, 2007). In order to understand better about early Chinese funerary art, there are several issues in particular which need to be discussed. The Chinese culture itself, the history of Chinese art, and as well the purpose of funerary art in this regards are all incredibly significant and critical issues, and by thoroughly examining and discussing all of these issues, we will be able to attain a more informed and knowledgeable understanding in regards to what Chinese funerary art is all about. This is what will be dissertated in the following. Chinese art has truly varied throughout history, and it has been divided into certain periods by the ruling dynasties of China in particular, and that includes the Yangshao, Dawenkou, Hongshan, Liangzhu, Longshan, Early Shang, Anyang, Eastern and Western Zhou, Warring States, and the Early Qin Dynasties. The difference in art is remarkable throughout each separate dynasty; the way that the art evolved, and the actual purpose and meaning of it as well, especially in regards to funerary art. In the earliest dynasty periods in China, the forms of (funerary) art were typically made from pottery and jade, "to which was added bronze in the Shang Dynasty" (Wikipedia, 2007). It was in early imperial China when porcelain was introduced into the art forms, and this is in fact why in English the word China has become associated with the most valuable and high-quality porcelain. The Shang Dynasty is actually considered as being the first dynasty of all, and inscriptions are one of the most significant art forms that took place during the time of this dynasty, and this meant inscriptions on bronze artifacts and oracle bones for instance, the oracle bones in particular which date back to the latter half of the dynasty, and these divinations can truly be considered as standing for various different things, including for giving information on the politics, economy, culture, and religion at that time. The Western Zhou Dynasty period was another which held incredible significance, and it was during this period in particular in which inscriptions became increasingly common and significant, and as well lengthier, and these were used to truly extol the achievements of the owner, as well as express the 'poignant wish' that the piece will not only be able to honor his forebears, but as well that he will be able to recall his own merits to his descendants, for 'generations without end'. The Yangshao Dynasty is yet another one of great importance in regards to the Chinese (funerary) art which was created during this time, and one of the most common forms of art in particular was that of swirling spirals and geometric designs, of which were often etched onto pottery wares. During the latter part of this dynasty, brush-painted pottery became incredibly popular, and it also became more sophisticated in regards to the way that it was completed, especially in regards to the handling of the design. The Dawenkou Dynasty is another important time period here for Chinese art, and during this period it was ceramics that were incredibly common and as well significant, and here as well inscriptions were used quite frequently,